Bristol-Myers Squibb, USA
Pharmaceutical Company Partners
Since 2004, IPM has negotiated five non-exclusive and one exclusive royalty-free license agreements, and one exclusive worldwide rights agreement from pharmaceutical companies to develop, manufacture and distribute nine antiretroviral (ARV) drugs as microbicides in developing countries.
These licenses ensure that any new product will be available at little or no cost to women in developing countries where incidence of HIV is especially high.
Compound | License | Mechanism of action | IPM development stage |
Dapivirine | Janssen Sciences IrelandÌýUnlimited Company (previously Tibotec) | ±·±·¸é°Õ±õ:ÌýReverse transcription |
|
DS003(BMS793) | BMS | ²µ±è120:ÌýCell attachment |
|
Janssen Sciences IrelandÌýUnlimited CompanyÌý | Protease inhibitor:ÌýProtein synthesis and assembly |
| |
Maraviroc | ViiV Healthcare | CCR5:ÌýCell Attachment |
|
Tenofovir | Gilead | NRTI:ÌýReverse transcriptionÌý |
|
DS001 (L167), DS004 (L872), DS005 (L882) | Merck | CCR5:ÌýCell Attachment |
|
DS007 (L-644 peptide) | Merck | gp41:ÌýCell fusion |
|
* Compound is in different stages of development by other organizations
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IPM continually seeks opportunities to work with pharmaceutical companies and other public and private sector research-based organizations and institutions to collaborate on developing promising microbicide and other HIV prevention products.
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IPM pharmaceutical partners
Gilead Sciences, Inc.,ÌýUSA
Janssen Sciences Ireland Unlimited Company
Merck & Co., Inc., USA
ViiVÌýHealthcare